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Unverified sources may contain degraded peptide fragments, incorrect amino acid sequences, or insufficient active compound, meaning stated dose doesn't match pharmacologically active dose

This quantal dose-response phenomenon is used to determine the median lethal dose ( LD 50 ) of drugs, as defined in Figure 41

Sep 24 2024;332(12):967-969

Ascorbate requirements of smokers based on intake and serum concentrations show that smokers may require as much as three times the dose of ascorbate than nonsmokers to avoid risk of efficiency [3032, 34]