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Steck E, Bertram H, Abel R, Chen B, Winter A, Richter W: Induction of intervertebral disc-like cells from adult mesenchymal stem cells

Since tropomyosins organize actin filaments and stabilize stress fibers, which are the primary structures sensing mechanical cues, we propose that tropomyosins may be involved in the fibroblasts ability to sense and respond to increased tissue stiffness

Stress, alcohol, pollution, and aging burn through it faster than you make it, which is where topping it up comes in

Although there are no human clinical trials on optimal dosing, we rely on animal literature and anecdotal evidence

PMID: 35057070 Neurosci Bull Neuronal and Glial YAP/TAZ in the Spinal Cord Contribute to the Development of Bone Cancer Pain in Mice