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Additionally, 15-d-PGJ 2 induces apoptosis in follicular keratinocytes, as evidenced by increased expression of the pro-apoptotic Bcl-2-associated X protein (BAX) and caspase 3, as well as decreased expression of the anti-apoptotic protein B-cell lymphoma 2 (Bcl-2) [181]

312 Platelets, which are responsible for approximately 90% of circulating A, 313 are overactivated with ageing 314,315 and are reported to release more A and subsequently induce A deposition in the brain and cognitive impairment

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Tools for intracellular zinc detection The accurate mapping of zinc within intracellular compartments is crucial for understanding its regulatory functions in organelle function, signaling and homeostasis