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Semaglutide, a glucagon like peptide 1 (GLP 1) receptor agonist, has well established weight loss benefits. Cagrilintide, a long acting analogue of the satiety hormone amylin, has shown promise for weight loss in early trials. The potential benefit NN1213 A Potent, Long Acting, and Selective Analog of Human Amylin Journal of Medicinal Chemistry Efficacy and safety of once weekly cagrilintidesemaglutide (CagriSema) in adults with type 2 diabetes inadequately controlled on diet and exercise (REIMAGINE 1): a randomised, double blind, placebo controlled, phase 3a study The Lancet Diabetes Yeah, so this sh*t works. :) [CagriSema Trial 1 yr details in comments] : r Semaglutide CagrilintideSemaglutide in Adults with Overweight or Obesity and Type 2 Diabetes New England Journal of Medicine

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