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4.3 Mitochondrial redox signaling as a bidirectional regulator of sleep and cellular homeostasis Mitochondria are the primary source of intracellular ROS, generating approximately 90% of cellular ROS as byproducts of oxidative phosphorylation (Balaban et al., 2005)

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GABA administration causes the GABA-shunt-related gene expression and activates the antioxidant enzyme system, which confers a tolerance to As (III) in rice seedlings when they are exposed to arsenic (As (III)) stress (Kumar et al