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Moreover, voltage-dependent anion-selective channel protein 1 (VDAC1)-mediated mitophagy has been also reported [55]

In addition, it has been demonstrated that ROS are also actively involved in the formation of NETs [109], autophagy [110,111,112], chemoattraction and activation of the inflammasome [113,114,115], programmed cell death of infected reservoirs [116, 117], antigen presentation, T-helper cell activation and lymphocyte proliferation [118,119,120,121]

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