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By contrast, while fibroblast growth factor (FGF) potential to induce skeletal muscle angiogenesis has been extensively investigated (for review see, i.e., [133]), the practical significance of such FGF, and even vascular endothelial growth factor (VEGF) [134], for muscle healing means an effect that is mostly limited to direct local administration combined with different modes of delivery [135]

Journal of Cosmetic Dermatology, 22 (1), 262-266

Now we have a drug that could be very important if its shown to work in clinical trials. The stapled peptide SP9 will be further refined before moving to human studies, as is typical for therapeutics at this stage of development, and may enter clinical trials in a couple of years

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In addition to these roles, ZIP7 promotes ERAD and, when pharmacologically activated, can reduce ER stress and rescue degeneration in models of protein misfolding 134