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A deficiency in B-12, or folate, can cause a wide range of problems, including: Fatigue and low energy Mouth ulcers Muscle weakness Pins and needles Problems with memory Psychological problems, which may include depression Sore, red tongue How does vitamin B12 impact testosterone

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Feature Vitamin Injections Oral Supplements Bioavailability Up to 100% (direct muscle absorption) Variable, often 10-50% (digestive system absorption) Speed of Action Rapid (hours to days for noticeable effects) Slower (days to weeks for noticeable effects) Ideal Candidates Diagnosed deficiencies, malabsorption issues, pernicious anemia, older adults, vegans/vegetarians with deficiency General maintenance, mild deficiencies, individuals with healthy digestion and absorption Administration Intramuscular injection by professional Pills, capsules, liquids taken by mouth For general maintenance in healthy people, oral supplements work fine

10.3390/biom9010034 110 PrzyborowskiK.WojewodaM.SitekB.ZakrzewskaA.KijA.WandzelK.et al (2015)