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Pregnant and breastfeeding individuals, those on anticoagulants or with bleeding disorders, and anyone with documented B12 toxicity (extremely rare) require provider consultation

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In addition, folic acid must be measured along with homocysteine because folic acid deficiency can cause the homocysteine level to rise.12 Management Low B12 levels are easily restored with B12 (cyanocobalamin) supplements

Understanding these recommendations helps prevent both deficiency and unnecessary over-supplementation

This is significantly shorter compared to other sealants which typically require anywhere from 4 to 24 hours of wait time before exposure to water