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Jakonbon, IN., A Steady-State-Kinetic Random Mechanism for Glutathione S-Transferase A from Rat Liver , (Received October 14, 1976/March 18, 1977 3

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Importantly, these toxicities are largely due to on-target effects of systemic mitochondrial uncoupling, which result in uncontrolled heat dissipation, decreased ATP production, and increased cytosolic calcium concentration, potentially eventually leading to death

Second, patients with chronic kidney disease (CKD) stages 3b through 5 may have impaired copper excretion through bile and urine [13]