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Pineyro G, Archer-Lahlou E: Ligand-specific receptor states: Implications for opiate receptor signalling and regulation

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Whether it produces meaningfully better outcomes than once-daily dosing in humans remains unknown

doi: 10.3390/pharmaceutics16030441 12

The treatment, which was previously indicated only for symptomatic children 3 years of age and older with late infantile CLN2 disease, also known as Batten disease, can now be given to diagnosed children of all ages, regardless of whether they are symptomatic or presymptomatic