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, 39 , 1010428317691429, doi: Espinosa-Diez, C., Fierro-Fernandez, M., Sanchez-Gomez, F., Rodrguez-Pascual, F., Alique, M., Ruiz-Ortega, M., Beraza, N., Martnez-Chantar, M

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Celecoxib We noted an immediate and then sustained effect on pressure in lower esophageal sphincter, and a postponed effect on pyloric sphincter after either 0.5 mg/kg or 1.0 mg/kg intraperitoneal challenge

The endoplasmic reticulum (ER) stress in the IECs promotes IBD mediated by the activation of p38 signaling pathway, and the activated TLR4 promotes the inflammation of IBD through ER stress-p38 MAPK signal pathway (Hu et al., 2022