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The mechanisms and regulation of autophagy and mitophagy have attracted considerable attention due to their impact in health and disease and have been recently reviewed (Ni et al., 2013)

Briefly, MDD patients were required to have a baseline HRSD 17 score 14, and all patients who completed 8 weeks of treatment ( n = 290) were treated with one of the two SSRIs, citalopram or escitalopram