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Beyond pathogen sensing, these receptors respond to elevated fatty acids and other obesity-associated molecular signals (373)

On the role of synthesized hydroxylated chalcones as dual functional amyloid- aggregation and ferroptosis inhibitors for potential treatment of Alzheimer's disease

The mitochondria are central to energy production in all cells and are affected by iron overload, leading to mitochondrial oxidative stress and participation in ferroptosis ( Recent studies have highlighted the role of mitochondrial calcium uniporters (MCU) in mediating iron-induced mitochondrial dysfunction