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When sulforaphane enters the cell, it interacts with Keap1, causing it to release Nrf2

Briefly, dried samples were resuspended in 100 l of 50 mM ammonium acetate (AA), after which excess NEM was removed using 300 l of dichloromethane

Furthermore, a reduction in cortical parvalbumin-positive interneurons, a hallmark of SZ, can also be triggered by NMDAR antagonists 14 , suggesting that they may be particularly vulnerable to NMDAR hypofunction (the relatively young age of the rats used in the current study prevented analysis of parvalbumin-positive interneurons since they are yet to develop)

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Schmieder S, Patel P, Krishnamurthy K