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111: 1734 Acknowledgements The authors state that no financial support or author involvement with organizations with financial interest in the subject matter exists, and that no actual or potential conflict of interest exists

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N -nitrosobutyl (4-hydroxybutyl) amine (BBN) causes urinary bladder carcinogenesis, and this effect was also suppressed through oltipraz in an Nrf2-dependent manner (Wang et al., 1999

B12 is safe on its own, but a few conditions call for extra care, which is why a provider reviews your history before treatment: Leber's hereditary optic neuropathy, a rare inherited eye condition, where certain forms of B12 may be a concern for the optic nerve