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Structural characteristics of effective siRNA molecules have been identified

Beyond generating ROS to induce ICD, more sophisticated structural designs can integrate multiple therapeutic modalities into a single COF platform, creating stronger synergistic effects to more effectively ignite the immune response

Consistent with the approach adopted in the FY 2023 IPPS/LTCH PPS final rule, for FY 2024, we are proposing to calculatethe average of FY 2019, FY 2021, and FY 2022 historical discharge data, rather than a 3-year average of the most recent 3 years of discharge data from FY 2020, FY 2021, and FY 2022

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The disruption of copper metabolism may mediate cytotoxic damage and induce tumor cell death, providing new strategies for cancer treatment