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Oral vitamin B12 supplementation after Roux-en-Y gastric bypass: a systematic review

Store the lyophilised vial cool, dry and protected from light prior to reconstitution

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Proper injection technique and site rotation minimize this risk

While the study concluded that short-term DSIP treatment was unlikely to be of major therapeutic benefit noting that statistically significant effects were weak and partly attributable to incidental placebo group change it provided the most methodologically rigorous human sleep architecture dataset for DSIP and confirmed the compounds specific effect on objective, not merely subjective, sleep quality parameters