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In ABCB1 overexpressed ovarian cancer cells, erastin co-delivery with docetaxel significantly reduced cell viability, promoted apoptosis, and induced cell cycle arrest at G2/M

Viral delivery of a microRNA to Gba to the mouse central nervous system models neuronopathic Gaucher disease

We appreciate the funding support of NIH-NHLBI (2R15HL143545-02)

Future research should also aim to disentangle the mechanistic interplay between S accumulation, sirtuin dysregulation, and impaired insulin signaling in PD, to identify which phytomolecules are most effective in counteracting mitochondrial stress, mitophagy defects, and neuronal apoptosis

Caution: If you are pregnant or nursing, consult your physician before taking this product