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At equal molar concentrations (based on the optimized amount for DDA), we found that both C10 and C12 (DDA) are equivalent and both induced a facile phase transfer while C4 did not

Toxicol Pathol 51:405413 Nuamah MF (2022) The study of troglitazone liver toxicity via in vitro and in silico approaches: University of Nottingham 2022 Vargas JNS, Hamasaki M, Kawabata T, Youle RJ, Yoshimori T (2023) The mechanisms and roles of selective autophagy in mammals

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These new findings encourage a novel working hypothesis for further research, that a chemical-modification mechanism enables transformation of HGF through interaction or reaction with LASSS under physiological conditions, resulting in the retention of HGFs biological activity after exposure to peroxynitrite, at least until an enhanced form of HGF undergoes metabolic turnover in vivo

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