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This metabolic vulnerability has been exploited as therapeutic modality where depletion of NAD+ using small molecule inhibitors targeting the salvage NAD+ synthesis enzyme nicotinamide phosphoribosyl transferase resulted in strikingly selective cytotoxicity in IDH1 mutant cancer cells [148]

Storage: store in a closed container at room temperature

Therefore, in a GSHcompromised system, the increase in the rate of formation of disulphide bonds is accompanied by an increase in the time required for isomerization

FlckigerUMarchettiOBilleJEggimannPZimmerliSImhofAet alTreatment options of invasive fungal infections in adults

Then, erythrocytes were prepared for fatty acid analysis [145]