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A precursor folic acid molecule must interact with the enzyme MTHFR (methylenetetrahydrofolic acid) to become 5-methyltetrahydrofolic acid, the molecule that donates its methyl group to B12 so it can become Methyl-B12

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Regulation of intermediary metabolism by protein acetylation

As mentioned earlier in Section 4.2.12, vitamin B13 has not been studied alone, but only in combination with other vitamins, as demonstrated in two studies of major interest in the AD context