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The drug release of PLGA-based nanoparticles and their application in treatment of gastrointestinal cancers

Overcoming the Limitations of Anthracyclines: Advances in Formulations and Combinations To mitigate the well-documented toxicities and resistance mechanisms associated with anthracyclines, particularly doxorubicin, researchers have developed innovative approaches aimed at enhancing therapeutic efficacy while reducing harm to healthy tissues

combination of mesolimbic and mesocortical pathway) is most relevant, due to its regulatory effect on motivation or wanting of food ( 4.2 D1R vs D2R The Counteractive Actions of the Two Dopamine Receptor Classes DA binds to and acts via two different receptor classes, the D1 receptor class (D1R and D5R) and the D2 receptor class (D2R, D3R and D4R)

The similarity of their iron dysregulation and ferroptosis phenotypes to human AD remains questionable, limiting the translational power of the conclusions