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With respect to VHE, Verrotti and coworkers [69] demonstrated an increase in glutamine production in astrocytes whereas glutamine release was inhibited

HLA, human leukocyte antigen

2017), these excitotoxicity-driven mechanisms ultimately lead to cognitive decline, epilepsy, and neurological deficits

This process, which ensures an adequate supply of free CoA, is essential for the oxidation of pyruvate and helps to coordinate pyruvate dehydrogenase activity with the rate of glycolysis, thereby maintaining the bodys ability to switch between fat and carbohydrate as the main energy substrate [9]

Pharmacists play an important role in educating patients on CS and AD medications