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Of the 11 plasma inflammatory and growth factors previously associated with VCD in long COVID at the recruitment, four months after mild COVID-19 4 , only CCL11 and LIF displayed a transcriptional upregulation in leukocytes from individuals with persistent impairment

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Composed of 15 amino acids, this pentadecapeptide has been shown in research to stimulate angiogenesis, collagen formation, and tissue remodeling.- It may interact with nitric oxide pathways, growth factor expression, and inflammatory cascades to support endothelial function and cellular recovery.- Suggested mechanisms include upregulation of VEGF, engagement with FAK-paxillin signaling, and protective effects under oxidative stress conditions