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[ In previous studies, it was demonstrated that UA significantly increased superoxide production in differentiated adipocytes

Overall, our data demonstrate that melatonin profoundly disrupts ILC2 metabolism

It is also questionable whether the increased concentration of succinate, as an effect of HIF-1 induction, generates in such conditions the reverse flow of electrons from cytochrome II to I, generating the strong electron leakage in cytochrome I, as described in (188)

GLS as a diagnostic biomarker in breast cancer: in-silico, in-situ, and in-vitro insights [J]

Conversely, a lack of SCFA-producing Roseburia and Faecalibacterium (often reduced in PD) means fewer Tregs to keep inflammation in check [163]