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2024 Jul 13];41(2):243-50

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Swiegers et al., 2007

For instance, overexpression of prostacyclin synthase or inhibition of miRNA-34a has been demonstrated to shift macrophage populations towards an M2 phenotype, reducing inflammation and enhancing tissue repair in experimental models of ALD.34 41 These findings highlight the therapeutic potential of targeting macrophage polarisation to balance pro-inflammatory and anti-inflammatory responses, offering a strategy to mitigate the liver damage caused by chronic alcohol consumption

In: Principles of Gynecologic Oncology Surgery