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Metabonomics analysis of quercetin against the nephrotoxicity of acrylamide in rats

Additionally, in FDX1 knockout experiments, there was a significant decrease in protein lipoylation of DLAT and another TCA cycle component called dihydrolipoamide S-succinyltransferase (DLST), both of which no longer bound copper, suggesting the necessity of lipoyl moiety for copper binding

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