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Choline is required to package fats into lipoproteins so they can be transported out of the liver and used for energy

Vitamin B12 is important for growth, cell reproduction, blood formation, protein and tissue synthesis

Oral B12 is broken down by stomach acid before it absorbs

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When stratified by administration route, the mean percentage changes were: Intramuscular (IM): 307% Oral: 285% Sublingual: 199% IM administration showed the highest average B12 increase, although oral and sublingual routes also yielded substantial improvements, supporting their use as effective and less invasive alternatives