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doi: 10.1186/s12984-021-00826-2, 97 ShengminW

CE, collision energy

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Occasionally, degradation creates compounds with different receptor interactions than the parent peptide

[2] That work reported a long half-life on the order of 159195 hours (about 78 days) consistent with once-weekly dosing, and it provided the first human safety and tolerability read on the cagrilintide-plus-incretin concept that later became CagriSema