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Although physical examination and laboratory evaluation of most men with ED may not reveal the exact diagnosis, clinical and biochemical evaluation presents an opportunity to identify comorbid conditions [328]

A meta-analysis focused on complex reproductive histories confirms that for women over 35 with DOR, PCOS, or those undergoing ART cycles, meta-analyses can show meaningful marker improvements, but evidence certainty remains low and effects vary by subgroup and duration

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doi: 10.1007/s00125-021-05435-1 18 XuJLloydDJHaleCStanislausSChenMSivitsGet al