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(ii) As a delayed regimen, the therapy (BPC 157 or saline (5 mL/kg)) was given as an intragastric administration at 4.30 h of ligation time for assessment at 5 h of ligation time, or BPC 157 as an oral administration, given continuously in drinking water from 5 h of ligation time until the sacrifice at 24 h of ligation time (0.16 g/mL/rat, 0.16 ng/mL/rat) while controls received drinking water only (12 mL/day/rat)

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Both BPC-157 and TB-500 have been studied in skeletal muscle injury and regeneration models with BPC-157 characterised as promoting muscle healing through angiogenesis, anti-inflammatory effects, and cytoprotective signalling that reduces ischaemic and inflammatory muscle cell death, and TB-500 characterised as promoting skeletal muscle repair through PI3K/Akt-mediated satellite cell activation and myocyte migration, angiogenic support of regenerating muscle, and actin cytoskeletal regulation thats fundamental to the morphological changes required for myogenic differentiation