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The ADI-R is a comprehensive interview administered to parents that provides a thorough assessment of individuals with ASD (44)

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These perturbations not only compromise intestinal barrier integrity but also exacerbate microinflammatory cascades through lipopolysaccharide (LPS) translocation, establishing a pernicious gut-kidney axis deterioration cycle. Furthermore, gut microbial dysregulation constitutes a cardinal pathogenic determinant in CKD-associated cardiorenal syndrome (CRS), with microbial metabolites such as TMAO compromising cardiac and renal functionality, precipitating inflammatory cascades and fibrogenesis (Zhao B

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By neutralizing free radicals and reactive oxygen species, glutathione helps to reduce oxidative stress in cells