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This paper is based on a presentation given at the Annual Meeting of the Society for the Study of Ingestive Behavior in July 2021 and provides a personal view on some of the milestones in the discovery of amylin as a constituent of pancreatic islet amyloid deposits, as a pancreatic beta-cell hormone, and on its role in physiology and pathophysiology

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However, when someone has type 4 hemochromatosis (which is more common than the other types), it affects ferroportin function, and excess iron can accumulate in tissues