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The data demonstrate that PBS-prepared LNPs exhibit acceptable colloidal stability for biological applications: diameter 179.5 nm (PDI 0.14, near-neutral zeta potential), while TM-LNPs and TL-LNPs showed larger sizes (248.9 nm and 222.2 nm, respectively)both within acceptable ranges for in vivo delivery ( 0.3, indicating instability and non-uniformity), and a zeta potential of about 10.9 0.9 mV

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Dual CD4-based CAR T cells with distinct costimulatory domains mitigate HIV pathogenesis in vivo