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Indeed, a study revealed that this compound attenuated the depressive-like behavior in stressed animals, mediating alteration in the hippocampal levels of anti-inflammatory and proinflammatory cytokines and inducing antioxidant actions, such as the modulation of SOD and CAT activities [86]

This function is analogous to that of ceruloplasmin in the circulation and brain: both HEPH and ceruloplasmin ensure that cellular iron release does not lead to toxic ferrous accumulation

Glutathione in the body aids in the fight against free radicals, and reduces oxidative stress

Consistently, the proliferation of Th1 and Th17 cells was found to be decreased (Figure S3)

These include genetic testing for variants in the MTHFR and other genes that affect methylation pathways, as well as blood testing for homocysteine levels