glutathione conjugation of acetaminophen Zonation drug metabolism in vitro. (a) Frontiers | Pharmacogenomics of acetaminophen

Oxidized protein disulfide isomerase (PDI) facilitates disulfide bond formation in conjunction with endoplasmic reticulum oxidase 1 (Ero1), while GSH acts as a buffer to maintain the reduced form of PDI [50]

Anegkamol et al., 2025)

Machine learning to establish three sphingolipid metabolism genes signature to characterize the immune landscape and prognosis of patients with gastric cancer

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and (b) data for metabolites, co-factors, genes and/or enzymes associated with the -glutamyl cycle or the trans-sulphuration pathway, and/or (c) interventions using metabolites or cofactors of the -glutamyl cycle or the trans-sulphuration pathway