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However, the high total-body content of glutathione (probably in the range of 40 to 80 gm in a 70 kg adult) and the relatively short half-life of this reactive and metabolically important compound (4 to 10 hours in most tissues) render glutathione replacement extremely difficult to achieve in practice

MicroRNAs in the regulation of cellular redox status and its implications in myocardial ischemia-reperfusion injury

A multiinstitutional survey of the Wiskott-Aldrich syndrome

Aminoacids (like serine) are major one-carbon sources, and cancer cells are particularly susceptible to the deprivation of one-carbon units by serine restriction or inhibition of de novo serine synthesis

Because the chronic diseases associated with GSH deficiency are also the leading causes of death today, it serves to reason that even small potential health benefits across many chronic illnesses would have a meaningful impact in decreasing population-wide morbidity and mortality