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Enzymatic or non-enzymatic, antioxidants are substances that prevent the formation of free radicals, and seek and neutralize or repair the damage caused by them ( ROS homeostasis is ensured by various antioxidant systems present both in plants (Sharma et al., 2012) and the human body (Hsu et al., 2000

ET-1 has since been found to govern a diverse range of homeostatic mechanisms in the body and is associated with several cardiovascular disease states ( A and ET B , have opposing actions that serve to modulate the effect of ET-1

Medrano, M., Racedo, S