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In 1956, a dermatologist named Alan Lyell described a mucocutaneous condition similar to but more severe than SJS, toxic epidermal necrolysis (TEN) or Lyells syndrome

Furthermore, longitudinal change in GSH mPFC (i.e., the difference between baseline and 6 months of NAC/placebo add-on treatment) correlates with the change in gFA along the fornix bundle in NAC patients and in NAC and placebo patients pooled together

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The increased understanding of ferroptosis enables us to interfere with key regulators to inhibit or induce this process, ultimately dampening liver disease progression and paving the way for new drugs

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