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4 Immunoprecipitation with a GST-p63-DBD probe confirmed that the RING E3 ligase Pirh2 bound to the p63 DBD and, to the authors knowledge, demonstrated for the first time that Cop1 did not bind to the p63 DBD and may not be a critical regulator of p63

The LOX inhibitor R2 has demonstrated significant activity, particularly in its (S, S)- 2 form, with a notably high negative value

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