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Additionally, proteins in this group exhibit binding affinities for small molecules (GO:0036094), carbohydrate derivatives (GO:0097367), and heterocyclic compounds (GO:1901363), underscoring their versatile roles in interacting with various biomolecules

Renal cells in the context of ADPKD exhibit a wide range of metabolic abnormalities, including the decreased expression of system Xc- and reduced activity of GPX4, which are the necessary conditions and typical characteristics of ferroptosis [252, 253]

10, e15183 10.14814/phy2.15183 [DOI] [PMC free article] [PubMed] [Google Scholar] 90.Habtemichael, E.N., Li, D.T., Alczar-Romn, A., Westergaard, X.O., Li, M., Petersen, M.C.et al

1,2 The number of patients with diabetes globally is expected to reach 783 million by 2045

Available from: Mode of Action (MOA) of Sulfonamide Antibiotics [Internet]