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However, opportunities to enhance ADSC therapy include the development of gene-modified ADSCs to overexpress angiogenic or neurogenic factors, the use of exosome-based therapies, and combining ADSCs with other regenerative techniques like low-intensity shockwave therapy

The above compositions may be prepared from aqueous solutions of peptide copper complexes

ALA may help correct several mechanisms involved in DPN, including sorbitol accumulation, microvascular damage, oxidative stress, and lipid peroxidation [16]

doi: 10.1016/j.cell.2020.12.025 219 MariniM.NiuY.ZhaoH.MohanA.KoorndykN.KruyerA.et al