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Neutrophils are characteristic of acute bacterial suppurative pneumonia, expressing pro-inflammatory cytokines 25,26

Preparation of the receptor grid for the docking procedure was performed by assigning the co-crystallized ligands as the centroid of the grid box in each PDB crystal structure using the receptor grid preparation module in Schrdinger (version 2019.1)

FDA approval Phase 1, 2 and 3 clinical trials require companies to perform extensive clinical studies to determine drug safety and efficacy

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For e , f , at least two independent experiments were carried out with similar results