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Silymarin reduced PGE 2 -induced CREB/Src-STAT3 phosphorylation, suggesting that its inhibitory effect on PGE 2 -induced cell migration may be related to the G protein-dependent PKA-CREB and G protein-independent Src-STAT3 signalling pathways (Woo et al., 2015)

B.MeleJ.et al

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To prepare the extract, fresh red-skin dragon fruits were obtained from an authentic local supplier, and washed thoroughly with distilled water to remove impurities