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Expression levels of S100A8 and S100A9 are significantly elevated in psoriatic keratinocytes and leukocytes, and their expression levels correlate positively with the severity of psoriasis (107)

Die meisten Menschen erleben keine oder nur sehr milde, vorbergehende Nebenwirkungen und profitieren erheblich von den positiven Effekten der Behandlung

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Adjibade M, Andreeva VA, Lemogne C, Touvier M, Shivappa N, Hbert JR, Wirth MD, Hercberg S, Galan P, Julia C, Assmann KE, Kesse-Guyot E

Thus, an increase in NRF2 activity, reflected by induction of NRF2 target genes, likely represent an important mechanism mediating the protection seen in GCLM KO mice