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Mol Pharmacol 59:349357 Fischer M, Falkensammer C (1977) New drug combination for medical management of hyperlipemia: clinical study

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10.1073/pnas.222546799 57 FremeauR

This ratio is in the range of 500

In locally advanced disease, such combinatorial approaches may theoretically enhance treatment responses in preclinical models, which could provide a conceptual basis for less invasive interventions