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BCL-2/adenovirus E1B 19-kDa interacting protein 3 (BNIP3) is an atypical BH3-only protein, whose divergent BH3 domain is not required for hetero-/homodimerisation and cell death in comparison to the other BH3-only proteins 12

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Cells were maintained in DMEM (HCT116, SW480, U2OS), MEM- with 1 ng ml 1 fibroblast growth factor 2 (Peprotech, hMSC) or DMEM with 1% non-essential amino acid (Gibco) and 50 g ml 1 uridine (Sigma-Aldrich) supplementation (143B), with 10% dialysed foetal bovine serum (dFBS), 50 U ml 1 penicillin and streptomycin (ThermoFisher, 15070063) and 1 mM sodium pyruvate (ThermoFisher, 11360070)

Food Bioproc Tech2026 Feb 16;19(4):166

Targeting macrophage polarization by inhibiting Pim2 alleviates inflammatory arthritis via metabolic reprogramming