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Research into artificial cells spans many disciplines and applications, generally focusing on top-down reduction of cells into nonliving protocells or bottom-up generation of complex systems

The ubiquitin-like modifier FAT10 is degraded by the 20S proteasome in vitro but not in cellulo

Park HK, Kim SM, Choi CG et al (2008) Effect of trientine on manganese intoxication in a patient with acquired hepatocerebral degeneration

As it relates to disease development, Liu and Guo (2012) reported aberrant expression of DNMTs in eutopic endometrium of patients with adenomyosis

All three together create a synergistic environment that, over time, can make each strand look a touch thicker