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GIP is also implicated in nausea attenuation, which may be why GLP-1/GIP dual agonists like tirzepatide have a slightly better GI tolerability profile than pure GLP-1 agonists

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This was the first demonstration that a GLP-1R agonist produces cardiovascular benefit independent of glycaemic effects, expanding the research interest in GLP-1R agonism beyond metabolic and weight endpoints

During repair, tubulin clusters are delivered and incorporated into polymerizing microtubules at the regenerating site

For GLP-1 agonists, periodic pancreatic enzyme levels (lipase, amylase) provide early warning of potential pancreatic issues